Influence of the intrauterine infection is on development of placenta disfunction

Abstract

DOI: 10.52705/2788-6190-2024-04.2-03
УДК618.3-07-08-06:618.33-022:618.36-008.6

The objective: a decline of frequency of obstetric and perinatal pathology is at the intrauterine infection of the fetus on the basis of study of features of the functional state of fetoplacental complex, system immunity and microbiocenosis of sexual ways and intestine, and also development and introduction of complex of treatment-and-prophylactic measures.
Materials and methods. By us 150 patients were inspected, among what 100 pregnant with a intrauterine infection, which were up-diffused on such groups: I group – 50 pregnant which got the generally accepted treatment-and-prophylactic measures; II group – 50 pregnant which got the method offered by us. A control group was made 50 primiparous, without obstetric and somatic
pathology, vaginal delivery. To the complex inspections were included clinical, laboratory, instrumental, morphological and
statistical methods.
Results. The use of the treatment-and-prophylactic measures, directed on the correction of hormone-synthesizing function of placenta, state of system and local immunity improvement of uteroplacental blood flow for pregnant at a intrauterine infection, offered by us was instrumental in activating of structural mechanisms of adaptation of placenta, maintaining of morphometric and
diffusive indicators of villous tree at the level of proof indemnification which is a major adaptive remedy for support of viability of fetus and prevention of his infection. It allowed to reduce frequency caesarean section in 2,3 times, premature ruptured membranes in 3,6 times, placenta disfunction in 1,9 times, fetal growth retardation in 1,7 times, fetal distress in 4,5 times, realization
of the intraamnial infection in 3,7 times.
Conclusions. The use of the algorithm of diagnostic and treatment-and-prophylactic measures improved by us allows to improve the results of delivery of women of group of high risk.