Tactic of treatment of infertility on a background a chronic urogenital infection for multiparous women

Authors

  • Makhmud Al' Fanir Shupyk National Healthcare University of Ukraine, Kyiv

Keywords:

infertility, urogenital infection, multiparous women

Abstract

DOI: 10.52705/2788-6190-2022-02-11
УДК 618.3-06:618.1-002

Do the results of the conducted researches testify that the changes of system immunity for multiparous patients with a chronic urogenital infection carry reliable not character, but violation of local immunity characterized by the reliable increase (р<0,05) of maintenance of IgМ and β-lysine at the simultaneous decline (р<0,05) of level of IgА; basic parameters of phagocytosis and lysozyme.
A chronic urogenital infection accompanies to development of violations of menstrual function in 32,0% cases and reliable dishormonal changes: in a 1 phase of menstrual cycle is a decline of maintenance of estradiol and follicle-stimulating hormone at the simultaneous increase of level of luteinizing hormone, aldosterone, cortisol and thyrotropic hormone; in II phase of menstrual cycle is a decline of maintenance of progesterone and increase of level of luteinizing hormone, cortisol and thyrotropic hormone.
The use of the offered treatment-and-prophylactic measures with subsequent pregravid preparation is instrumental in the increase of frequency of offensive of pregnancy in 2,1 time and to the decline of level of obstetric and perinatal complications: premature births – in 2,1 time; to placenta disfunction – in 1,5 time; anomalies of childbirth – in 2,1 time; fetal distress – in 1,6 time; middling-heavy forms of asphyxia new-born – in 1,7 time and perinatal losses – in 2,1 time.
Decline of frequency of obstetric and perinatal complications for multiparous women with a chronic urogenital infection in anamnesis it is needed to begin with the stage renewals of genesial function with the next passing to pregravid preparation. Taking into account circumstance that the women of this group have a high risk of the intra-amniotic infecting, predefined by the whole complex of negative influence from the carried urogenital infection basis of next obstetric and perinatal complications.
The got results appeared a convincing enough ground for developed by us treatment-and-prophylactic method. A substantial increase of frequency of renewal of genesial function on a background the decline of frequency of obstetric and perinatal complications is foundation for wide introduction of the offered method in a practical health protection.

Author Biography

Makhmud Al' Fanir, Shupyk National Healthcare University of Ukraine, Kyiv

Department of obstetrics, gynecology and perinatology of Shupyk National Healthcare University of Ukraine, Kyiv.

Published

27.06.2022

How to Cite

1.
Аль Фанір М. Tactic of treatment of infertility on a background a chronic urogenital infection for multiparous women. par [Internet]. 2022 Jun. 27 [cited 2022 Nov. 26];2(2):72-7. Available from: http://par.org.ua/index.php/par/article/view/79