Women have comparative aspects of pregnancy and births with infertility of different genesis

Abstract

DOI: 10.52705/2788-6190-2022-04-11
УДК 618.177-02:618.3/.5

The objective: of comparative aspects of clinical motion of pregnancy and perinatal consequences
of delivery for women with infertility of different genesis.

Materials and methods. 90 patients with infertility in anamnesis, pregnancy were inspected in
which came as a result in vitro fertilization. In a 1 group 30 patients entered from tubal peritoneal
infertility, in a that number 13,3% with absolute tubal infertility (absence of both salpinxs). 2
groups were made by 30 patients with endocrine infertility in anamnesis. In 3 groups 30 patients
are plugged with the masculine factor of infertility.
The analysis of consequences of pregnancy was conducted depending on a gestational term in
comparison with which distinguished: pregnancy that does not develop and spontaneous abortion
in I trimester, late spontaneous abortion in II trimesters, premature births from 28 to 34 weeks
gestation, premature births in a term 34–37 weeks, births at term. Considered the consequences
of pregnancy unhappy at presence of genesial losses in I and II trimesters, and also premature births. The results of researches worked over the method of variation statistics with the use of
self-reactance and non-parametric methods.

Results. At differential approach taking into account etiology of infertility, it is set by us, that highfrequency
of delay of growth of fetus is characteristic only for the patients of endocrine infertility in
anamnesis (23,3%), while frequency of this complication at tubal peritoneal infertility in anamnesis
was 6,7%, and at masculine infertility was within the framework wildly popular general population
(3,3%). At the same time this frequency from data of literature makes from 18% to 29,3%, that in
6–9 times higher than in population (27-th World Congress of Fertility and Sterility, 2019).
Information is got by us disagree with literary, that can be also to explain absence of multifetations.
Burdened obstetric and gynaecological and somatic anamnesis, complications of motion of
pregnancy for patients after in vitro fertilization determine the method of delivery.
In this research, regardless of reason of infertility, frequency is C-section was 32,3%, that in
2–3 times below that pointed in literature (27-th World Congress of Fertility and Sterility, 2019 –
71,9%), so as in research the patients of took part by singleton pregnancies.

Conclusions. Genesial losses and complications of pregnancy in a greater measure are conditioned
by genesis of infertility. In addition, on motion and investigation to a I trimester, regardless of reason of
infertility, such complication of stimulation of ovulation creates unhappy influence, as a syndrome of
overstimulation of ovaries. Hormonal violations are expressed in early terms (both near-term existing
and iatrogenic) create pre-conditions for development of complications in more late terms of pregnancy
(threat of breaking, isthmic-cervical insufficiency, preeclampsia, fetal growth retardation).
In spite of the fact that patients after in vitro fertilization make the group of high risk in relation
to miscarriage and premature births, at adequate individual approach possible achievement of
high-purity of happy consequences – «take home baby». The individual going near the choice of
method of delivery taking into account reason of infertility in anamnesis will serve to the decision
of actual task of modern obstetrics – decline of frequency C-section.