Characteristics of the hormonal profile of peripheral blood serum in injured veterans with disorder of reproductive function

Authors

  • Anastasia Serbeniuk Shupyk National Healthcare University of Ukraine, Kyiv

Keywords:

reproductive health, female veterans, post-concussion syndrome, endometrial receptivity, follicular phase, luteal phase, hormonal profile

Abstract

DOI: 10.52705/2788-6190-2023-01-05

Today, more than 30,000 women serve in the Armed Forces of Ukraine. According to statistical data, the number of people with post-traumatic stress disorder is 27.7% among military personnel who took part in active combat operations. Post-traumatic syndrome is a frequent predictor of various conditions with changes in the hormonal background, morpho-functional changes of the endometrium, which in turn has a negative impact on women’s reproductive health.
The objective: to study the peculiarities of the hormonal profile in women of reproductive age who took part in combat operations and suffered a concussion.
Materials and methods. The study of the peculiarities of the hormonal profile was carried out in 457 women of reproductive age who took part in combat operations and suffered a concussion.
Of these women, 246 patients – the comparison group – of reproductive age with a history of trauma without post-concussive syndrome and 211 in the main group, women of reproductive age who have consequences of concussion in the form of post-concussive syndrome. 30 conditionally healthy civilian women of reproductive age served as controls.
Results. In women of reproductive age who took part in combat operations and suffered a contusion in the early follicular phase of MC, the level of FSH increased by 1.11 times, LH – by 1.32, and the ratio of LH/FSH – by 1.22 times compared to the control group; E2 – 1.25 times and Tf – 1.36 times.
In the period of ovulation, the average level of FSH is 1.14 times lower, and LH is 1.25 times lower.
Distinctive features of the hormonal profile of the peripheral blood serum in the mid-luteal phase of MC are that the concentrations of FSH and LH do not have probable discrepancies with the corresponding control indicators.
Conclusions. In patients with a history of concussion and with post-concussion syndrome, changes in the hormonal profile of peripheral blood serum are more pronounced than in women without post-concussion syndrome.

Author Biography

Anastasia Serbeniuk, Shupyk National Healthcare University of Ukraine, Kyiv

obstetrician-gynecologist, Clinic of Reproductive Technologies,
Ukrainian State Institute of Reproductology, Shupyk National Healthcare University of Ukraine,
Kyiv.

Published

25.03.2023

How to Cite

1.
Сербенюк А. Characteristics of the hormonal profile of peripheral blood serum in injured veterans with disorder of reproductive function. par [Internet]. 2023 Mar. 25 [cited 2024 Jul. 15];3(1):44-51. Available from: http://par.org.ua/index.php/par/article/view/108