Influence of assisted reproductive technologies is on clinical motion to a 1 trimester of pregnancy

Abstract

DOI: 10.52705/2788-6190-2024-02-15
УДК 618.3-036.1-06:618.177-089.888.11

The objective: to learn the comparative aspects of clinical motion of pregnancy for women after
assisted reproductive technologies at infertility of different genesis in anamnesis.
Materials and methods. 160 patients with infertility in anamnesis, pregnancy were inspected in
which came as a result in vitro fertilization. In 34 from 160 patients after transference of embryos
the noted development of ovarion hyperstimulation syndrome of different degree of severity. All
patients were up-diffused on groups depending on the etiologic factor of infertility.
Results. By us found out factors which are instrumental in reproductive losses in a 1 trimester
of pregnancy for patients from pipe peritoneal by infertility in anamnesis: low body mass index,
primary character of infertility and his duration more than 5 years, inflammatory genesis of
impassable salpinxs. Additional factors of risk of reproductive losses in a 1 trimester at masculine
infertility discovered it was not. It is set that in 2 from 3 patients pregnancy intermitted in 5–6
weeks on a type that stopped beating (anembryony). This fact, probably, is explained by inferiority
of spermatozoa which are entered in the cytoplasm of ovule, forming genetically of anomalous
embryos and is to the reflections of natural selection.
Conclusion. The results of the conducted researches testify that early terms of pregnancy are
«critical» for patients with infertility in anamnesis, regardless of his reason characterized by higher
frequency of reproductive losses and threat of breaking as compared to II and by III trimesters
of pregnancy. The risk of unfavorable result rises at development of ovarion hyperstimulation
syndrome. The got results must be taken into account at development of algorithm of diagnostic
and treatment-and-prophylactic measures.