Heavy form of placenta disfunction: early diagnostics and tactic of conduct of women

Abstract

DOI: 10.52705/2788-6190-2024-03.1-03
UDC 618.36-008.64-07-08

The objective: to develop the modern method of early diagnostics of heavy forms of placenta disfunction.

Materials and methods. Taking into account clinical motion of pregnancy, from 100 women two
groups of comparison were formed: I group was made by 50 women with placenta disfunction; II
group – 50 women with placenta disfunction in combination with preeclampsia and by extragenital
pathology. A control group (III group) was made 30 healthy expectant mothers. In the II group of
comparison of preeclampsia diagnosed in 100% supervisions (easy degree – in 88,0% pregnant
and middle degree – in 12,0%). In research the pregnant joined with the negative results of clinical
and laboratory inspection on a urogenital infection.
Results. Application of the developed methods, which represent the state of the basic biological systems which take part in forming of placenta disfunction, allows in good time to diagnose not only development from the II trimester of pregnancy but also it heavy forms, that at complex diagnostic approach (prognostic scale of factors of risk of decompensation; laboratory testing)
enables in good time to begin preventive treatment.
The got results allowed nosotropic to ground including of the developed criteria and degree of
its severity, together with an ultrasonic constituent, in the diagnostic of this complication of pregnancy program with the purpose of increase of its exactness. Results of early diagnostics and estimation of degree of its severity during pregnancy, based on the laboratory and ultrasonic testing (modified scale), in comparison with the histological verified diagnosis rotined that diagnosis placenta disfunction correctly put in 91% supervisions, divergence was 9%. The analysis of coincidence of clinical and histological diagnoses at heavy forms rotined an increase to exactness of diagnostics at the use of the modified scale on 39,5% as compared to the use of scale, based only on ultrasonic criteria.
Conclusions. The clinical algorithm of conduct of expectant mothers of risk group developed on the basis of evaluation diagnostic scale (ultrasonic and laboratory testing) is promoted by exactness of diagnostics of placenta disfunction on 26,1%, it heavy forms on 39,5%, instrumental in the choice of adequate obstetric tactic, to the improvement of perinatal results at the heavy forms
of placenta disfunction on 60%.
The got results allow to recommend the method of early diagnostics of heavy forms of placenta disfunction in a practical health protection.