The women of premenopausal period have features of pathology of endometrium with thyroid pathology
Keywords:
pathology of endometrium, thyroid pathology, premenopausal period, diagnostics, treatmentAbstract
DOI: 10.52705/2788-6190-2024-03.1-11
UDC 618.14-002:618.3:616.441
The objective: the women of premenopausal age have a study of nosotropic value of parafunctions
of thyroid in development of hyperplastic processes of endometrium.
Materials and methods. Research of structure and function of thyroid was conducted at pathology
of endometrium. In this research 149 women of premenopausal age, including 39 patients,
were plugged with high-differentiated adenocarcinoma of endometrium of the 1а stage (middle
age of 50,8±3,0 year; body mass index – 28,2±2,1 kg/m2); 34 patients with atypical hyperplasia
of endometrium (middle age of 50,1±2,4 year; body mass index– 28,6±2,3 kg/m2) and 39 patients
from glandular-cystic hyperplasia of endometrium (middle age of 48,9±2,2 year; body mass index–
26,6±2,4 kg/m2). A control group was made by 37 healthy women (middle age of 49,1±2,3
year; body mass index– 26,6±2,4 kg/m2).
Results. For women the comparable volume of thyroid, and also comparable prevalence of goitre
(the volume of thyroid more than 18 mm) and nodules, was determined in the inspected groups.
In all cases of found out the nodules of thyroid, speech went about nodes which do not exceed
3 sm in a diameter, and from results of fine-needle aspiration biopsy – about different degree of
proliferation of colloid nodular goitre.
Information of our research testify to absence statistically meaningful differences of prevalence of
different forms of goitre in basic and control groups. In addition, they answer that high prevalence
of goitre in the regions of iodic deficit, which all territory of Ukraine behaves to. By ultrasonic research
of thyroid the different forms of goitre in iodine deficiency regions can be found out in third
of the adult population.
Conclusions. The results of the conducted researches testify that nosotropic connection absents
between the parafunctions of thyroid, different forms of goitre and pathology of endometrium
(hyperplastic processes and cancer). The estimation of prevalence of diseases of thyroid among
women with hyperplastic processes and cancer of endometrium does not allow to examine violation
of its function as factor of risk of development of this pathology.
Treatment and supervision of patients with hyperplastic processes and cancer of endometrium
must be conducted the diseases of thyroid in obedience to the traditional charts of treatment as
combination of two different and not associate diseases.
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