Features of protein syntesizing function of placenta are at the preterm rupture of membranes on a background a urogenital infection

Abstract

DOI: 10.52705/2788-6190-2024-04.1-04
УДК 618.36:618.39

The objective: estimation of the state of protein syntesizing function of placenta for pregnant with the preterm rupture of membranes in the different terms of pregnancy.
Materials and methods. Complex prospective is conducted randomized clinical-and-laboratory inspection is conducted in 217 pregnant which motion of pregnancy became complicated by the preterm rupture of membranes in the term of gestation 22,5–33,5 weeks pregnancies with the estimation of the state of new-born.
In total sample the pregnant were included also and them new-born which were on an inspection and treatment in subsections of intensive therapy and reanimation. For diminishing of influence of casual factors by systematization of distributing of signs which was studied in an elector, for it the pregnant were not included with other obstetric complications: preeclampsia, multifetation,
disease of the cardiovascular system, endocrine system in the stage of sub- and decompensations which would influence on the results of researches. Concentration of specific placenta albumens: trophoblastic beta-glycoprotein determined a immunoenzyme method in the critical terms of gestation (5–14, 16–26 and 30–36 weeks pregnancies, with an interval in 1-2 weeks in the first
trimester, 4 weeks – in the second and third trimesters).
Results. At determination of placenta albumens additional possibilities of timely diagnostics of violation of the state of fetus and function of placenta appear in the whey of blood, that in connection with other methods is basis of decline of perinatal morbidity and death rate. Taking into account the wide enough limits of individual vibrations of placenta albumens in the
whey of blood in the process of development of pregnancy, and also some day’s vibrations of their levels, more reliable and perspective for diagnostics of the intrauterine fetal suffering equal determination of concentration of placenta albumens can serve in the whey of blood.
Conclusions. The got results it must draw on during the conduct of diagnostic and treatment-andprophylactic measures for women with a urogenital infection.