Women have features of different forms of endometriosis with hypofunction thyroid

Abstract

DOI: 10.52705/2788-6190-2024-04.1-12
УДК 618.1-007.415-092-036.1-06:616.441-008.64-08

The objective: an increase of efficiency of treatment of genital endometriosis in combination with a hypothyroidism and decline of frequency of relapse is on the basis of improvement and introduction of algorithm of diagnostic, treatment-and-prophylactic and rehabilitation measures with the use of modern endoscopic technologies and medicinal correction.
Materials and methods. By us was the conducted analysis of frequency of extragenital pathology in 789 patients with external genital endometriosis. On a 1 stage by us it was inspected 110 patients of reproductive age from 20 to 41 year with external genital endometriosis. All women were updiffused on two groups: a to 1 group entered 50 patients with external genital endometriosis without pathology of thyroid, in 2 – 60 women with external genital endometriosis and concomitant hypothyroidism. On 2 stages by us it was inspected 100 patients in a reproductive period with the different degree of prevalence of external genital endometriosis, in which were testimonies for operative treatment. A diagnosis all patients had confirmed during laparoscopy, and also as a
result of obligatory histological research. The clinical, laboratory, instrumental, functional, morphological and statistical methods of research were plugged in the complex of the conducted researches.
Results. At operative treatment of combination of genital endometriosis and hypothyroidism organpreserving operations are conducted in 55,0% women; in 45,0% – radical; in 56,0% laparoscopy is used and hysteroscopy; in 42,0% – laparoscopic-vaginal access and only in 2,0% is laparotomy. In addition, the defeats of sigmoid of colon and urinary organs take place in 10,0% cases. Frequency of relapse after operative treatment of genital endometriosis for women with a hypothyroidism makes through 6 – 6,0%; through 9 – 10,0% and in 12 months – 13,0% respectively. It is set at the analysis of variant of medicinal correction and duration of relapse-free course of genital endometriosis, that due to an antirecurrent hormonotherapy by preparations by the agonists of gonadotropin-releasing hormone, by courses not less than 6 months, duration of remission is substantially increased (on 30,8%) in comparing to other variants.
Conclusions. The results of the conducted researches testify that presence of concomitant hypothyroidism for patients with external genital endometriosis and treatment conducted after different methods, it is necessary to take into account at development of tactic of conservative treatment, preoperative preparation and postoperative against recurrent therapy with the use of basic hormonal preparations. Introduction of the got results will allow to promote efficiency of treatment both conservatively, and operatively, that will promote quality of life of women of reproductive age.