Women have features of forming and functional state of fetoplacental complex with the complicated reproductive anamnesis

Abstract

DOI: 10.52705/2788-6190-2024-04.2-15
УДК 618.177-089.888.11-06:616-053.31-036.1

The objective: to learn the features of forming and functional state of fetoplacental complex for women with the complicated reproductive anamnesis.
Materials and methods. In basis of work a complex inspection is fixed 100 pregnant after assisted reproductive technologies and them new-born (basic group). Group to comparison made 50 women of analogical age, in which pregnancy came in natural way. Middle age of pregnant in groups after assisted reproductive technologies made 29,0 ± 4,1 years and 33,1 ± 3,3 for men.
The protracted sterile period results in a volume, that the most favourable age missing for the offensive of pregnancy, and it comes in a late reproductive period on a background somatic and gynaecological diseases which accumulated. In the complex of the conducted researches were included clinical, echographic, doppler cardiotocographic, and endocrinological methods.
Results. From complications of the third trimester of pregnancy placenta dysfunction which had statistically reliable differences and was 62,0% in a basic group appeared major. It can be conditioned by that development of the induced pregnancy in the conditions of primary placenta dysfunction results in violation of outflow of blood from a placenta, to the insufficient entering of blood into intervillous spaces as a result of peripheral spasm, endotheliosis and thrombosis of vessels. The fetal growth retardation (27,0%) and fetal distress appeared the clinical displays of placenta dysfunction (24,0%). Preeclampsia of easy and middle degree of severity developed in 49,0% in a basic group. In addition, in the third trimester there was pathology of amount of amniotic fluid in the same group, so the oligohydramnios fixed in 18,0%, and a polyhydramnios is in 10,0% patients.
Conclusions. The got results testify to the necessity of development of algorithm of diagnostic and treatment-and-prophylactic measures with a purpose to the improvement of perinatal results of delivery.