Tactic of treatment of infertility for women with combined pathology of uterus and mammary glands

Abstract

DOI: 10.52705/2788-6190-2022-03-8
УДК 618.17/.5-02:618.145

The objective: is a decline of frequency of violations of genesial function for women withcombined pathology of uterus and mammary glands on the basis of study of new aspects ofpathogeny of infertility, and also improvement and introduction of algorithm of diagnostic andtreatment-and-prophylactic measures depending on the variants of combined pathology of uterusand mammary glands.

Materials and methods. Treatment of infertility all patients had conducted by the use of methodsof auxiliary genesial technologies. a 1 group was made by 90 women with diffuse dysplasia ofmammary glands. Among them three sub-groups of women were selected taking into accountthe presence of concomitant genital pathology. In the complex of the conducted researcheswere included clinical, echographic, doppler, cariotocographic, morphological, endocrinology,biochemical and statistical methods.

Results. By leading reasons of infertility women with combined pathology of uterus and mammaryglands have a presence of combined factors (tubal-peritoneal, endocrine, fallopian and masculine)– 48,9%; only fallopian – 20,0% and endocrine – 7,4%. In 23,3% cases reasons of infertility arenot set finally. The secondary infertility prevails in the structure of violations of genesial function –53,3% by comparison to primary – 46,7%. By the basic method of treatment of infertility women with combined pathology of uterus and mammaryglands have operative, here a middle amount of operations on one woman is 1,5±0,7; hysteroscopyprevails in a structure – 66,7% by comparison to laparoscopy – 20,0% and laparotomy – 13,3%.Efficiency of the programs of auxiliary genesial technologies for women with combined pathology of uterusand mammary glands does not depend on application of different charts of stimulation of ovaries, use ofauxiliary hatching, and depends on the state of ovarian reserve and timely use of oocyte of donor. Totalefficiency of treatment of infertility for women from of high quality dysplasia of mammary glands is 53,3%; atcombination with adenomyosis – 33,3% and with the leiomyoma of uterus – 30,0% respectively.

Conclusions. The use of the improved algorithm of treatment-and-prophylactic measures forwomen with combined pathology of uterus and mammary glands allows substantially to decreasefrequency of violations of genesial function.