Patients have a prophylaxis and treatment of diseases of mammary glands after hysterectomy

Abstract

DOI: 10.52705/2788-6190-2025-4-07
УДК 618.14-006.36-089.85-089.168.1-06:618.19-084

The objective: to develop and inculcate the method of prophylaxis and treatment of diseases of mammary glands for patients after hysterectomy.
Materials and methods. By us it was inspected 156 patients by a uterine fibroids, which is a basic certificate for implementation of hysterectomy. All patients with a uterine fibroids depending on age parted on 2 clinical groups: a 1 group was 67 patients which was added hysterectomy in late reproductive age (36–44 years, on the average in 40,9 ± 0,9 year); to 2 groups entered 89 patients which are operated in premenopause (45–47 years, on the average in 45,9 ± 0,2 year). A control group was made 20 practically healthy women of analogical age. To the complex of the conducted researches clinical, laboratory, instrumental and statistical methods were included.
Results. Objectively the positive dynamics of treatment was traditionally determined at a review, palpation and ultrasonic research of mammary glands. By the criteria of positive effect of reception a indole-3-carbinol was served: diminishing of edema, sickliness, heterogeneity of structure of mammary glands, decline of echogenicity tissue, diminishing of size of cysts in a diameter on 2–3 mm (from 0,5–1,2 mm to 0,3–0,9 mm) and diameter of mammary channels, improvement of expressed connecting tissue pattern. An effect from the use of preparation developed gradually, arriving at a maximum in 6 months after the beginning of reception. The best effect from treatment in 3 months of reception a indole3-carbinol was marked for patients diffuse fibrocystic mastopathy with predominance of cystic component. On the whole objective positive dynamics, through 3 and 6 months after the beginning of treatment marked in 72,5% and 91,3% patients respectvely. In 7 (8,7%) patients diffuse fibrocystic mastopathy with predominance of fibrotic component, without regard to the established subjective diminishing of pain syndrome, objectively any dynamics it was not discovered.
Conclusions. Preparations on basis a indole-3-carbinol is effective targeted therapy for patients with the different forms of diffuse fibrocystic mastopathy after surgical treatment of uterine fibroids in the volume of hysterectomy. As a diffuse form is the initial stage fibrocystic mastopathy, the timely nosotropic grounded treatment will prevent progress of disease in noncommunicative forms, that will reduce the risk of development of cancer of mammary glands in the end. The methodology is accessible and can be recommended for use in practical healthcare.