Women, operated concerning the ovarian tumours, have features of assisted reproductive technologies

Abstract

DOI: 10.52705/2788-6190-2025-4-14
УДК 618.11-006-089.168.1-06:618.177.886.11-039

The objective: to estimate influence of operative interferences concerning the ovarian tumours on the results of assisted reproductive technologies.
Materials and methods. From 342 patients with infertility 143 women (57,5%) had in anamnesis operative interferences on the appendages of uterus, 288 cycles in vitro fertilization - transplantation of embryos completed and made the basic group of research (group 1). Operative interferences were executed: 58 (41%) patients in anamnesis took place to the operation on ovaries; 37 (26%) patients in anamnesis took place to the operation on salpinxs; to 48 (33%) patients the united operations were conducted on ovaries and salpinxs. A basic group (group 1) parted thus: a 1А group is patients (73) which had in anamnesis operations on ovaries concerning tumor-like formations. On the basis of study of gynaecological anamnesis this group parted on 3 sub-groups. A control group (2А) was made by 106 women which appealed to the that interval of time in the separation of assisted reproductive technologies and in which during an inspection and preparation to procedure in vitro fertilization were found out different tumor like formations in one or both ovaries. The small size of cysts, duration of infertility, refuse of women, from an operation was allowed to this cohort of women to conduct the program in vitro fertilization without previous surgical treatment. This group similarly parted on 3 sub-groups. To the complex of the conducted researches were included clinical, laboratory instrumental and statistical.
Results. The real results demonstrate, that prehumulone surgical treatment of tumular formations of ovaries for patients with infertility worsens the results in vitro fertilization. Patients with operations on ovaries in anamnesis had less of follicles, oocytes at the greater amount of ampoules of exogenous gonadotropins, necessary for induction of ovulation. Low results in vitro fertilization for patients with operations in anamnesis it is possible to explain that during an operation there is an irretrievable loss of genetic (ovarian supply) ovary. Moreover, in time and after an operation, possible worsening of blood supply of ovaries, which results in diminishing of stimulation of ovaries endogenous gonadotropins.
Conclusions. Efficiency in vitro fertilization for women with infertility and operations on ovaries in anamnesis depends on quality of previous operative interference, and factors which promote authenticity of offensive of pregnancy is an adequate volume, careful technique of operative treatment, waiver of temporizing tactic and conduct in vitro fertilization after completion of surgical treatment.